Get Answers To The Questions You Have About Xeomin

FREQUENTLY ASKED QUESTIONS

HOW CAN I SAVE?

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HOW LONG IS THE RECOVERY TIME AFTER TREATMENT?

Treatment requires minimal downtime. So you can return to your daily routine immediately after you leave your provider’s office. Talk to your provider about what to expect after treatment.

DO I NEED TO BE OVER 40 TO START?

Age does not dictate when you can start Xeomin. When you start to notice lines (frown lines, forehead lines, or crow’s feet), speak with your provider to determine if Xeomin is right for you. Xeomin is indicated for upper facial lines in adults, when you start your treatment journey is entirely up to you and your provider.

WHAT IS XEOMIN®?

Xeomin® (incobotulinumtoxinA) is a prescription medication injected into muscles and used to temporarily improve the appearance of moderate to severe frown lines, forehead lines and crow’s feet in adults. Xeomin® contains botulinum toxin type A, a protein purified from the bacterium Clostridium botulinum.

WHAT IS SMARTTOX?

Xeomin is a smart toxin with a double-filtered formula that removes unnecessary ingredients. It’s designed to reduce the risk of treatment resistance (when you end up needing more units overtime to get the same results) and delivers consistent results.*

HOW DOES XEOMIN® WORK?

When you make certain facial expressions, the muscles in your face contract, causing the skin to furrow and fold. Over time, as your skin ages and loses some of its elasticity, these repeated contractions can cause persistent lines. IncobotulinumtoxinA – the active ingredient in Xeomin – acts on nerve endings in muscles to prevent muscle fibers from contracting. By reducing these contractions, Xeomin can temporarily reduce visible frown lines, forehead lines and crow’s feet.

IS XEOMIN® FDA APPROVED?

Xeomin received FDA approval for use in frown lines in 2011, and received FDA approval in 2024 for treating upper facial lines, which includes frown lines, forehead lines and crow’s feet.

WHAT SHOULD I TELL MY DOCTOR BEFORE TREATMENT?

Before receiving treatment with Xeomin®, you should tell your doctor about all of your medical conditions, including whether you have a disease that affects your muscles and nerves, have allergies to any botulinum toxin product, or have experienced any side effect from any other botulinum toxin in the past. In addition, tell your doctor about your medical history and all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. Especially tell your doctor if you have received any other botulinum toxin product in the last four months or in the past. Be sure your doctor knows exactly which product(s) you received and when you received them.

WHAT CAN I EXPECT DURING TREATMENT?

During treatment, your provider will inject Xeomin into the muscles where your results are desired (frown lines, forehead lines and/or crow’s feet). Most treatments take about 15-20 minutes. Remember to talk to your health care provider if you have any questions or concerns! Treatment requires minimal downtime. So you can return to your daily routine immediately after you leave your provider’s office.

HOW DO I KNOW IF XEOMIN® IS RIGHT FOR ME?

If you are an adult with moderate to severe frown lines, forehead lines, or crow’s feet, Xeomin® may be right for you. Talk to your doctor to discuss the benefits and risks of treatment. Do not use Xeomin® if you are allergic to botulinum toxin or any of the other ingredients in Xeomin®. You should also not use Xeomin® if you have had an allergic reaction to any other botulinum toxin product or have a skin infection at the planned injection site.

CAN I GET TREATED FOR MULTIPLE AREAS AT THE SAME TIME?

You can treat your frown lines, forehead lines and crow’s feet all in one appointment! Talk to your provider to discuss what is best for you.

HOW IS XEOMIN DIFFERENT FROM OTHER TOXINS?

Other toxin formulations have unnecessary ingredients that may cause treatment resistance (when you end up needing more units over time to get the same results). Xeomin is the first and only double-filtered upper facial lines treatment with no unnecessary ingredients, meaning it only has the ingredients needed to treat your frown lines, forehead lines, and crow’s feet!*

WHEN CAN I EXPECT TO SEE THE RESULTS?

You may begin to see visible smoothing as early as 3-4 days after injection. The median first onset of effect was less than a week. The maximum effect occurred at 30 days. The typical duration of effect was up to 3 months in clinical trials but may vary from patient to patient.

HOW MANY UNITS CAN/SHOULD I RECEIVE?

The total recommended Xeomin dose for treatment is 20 units for frown lines, 20 units for forehead lines and 24 units for the crow’s feet for a total of 64 units. Talk with your provider to see what is right for you!

WHAT ARE THE MOST COMMON SIDE EFFECTS OF XEOMIN®?

Xeomin® may cause serious side effects, including allergic reactions. Symptoms of an allergic reaction to Xeomin® may include: itching, rash, redness, swelling, wheezing, asthma symptoms, or dizziness or feeling faint. Tell your doctor or seek medical help right away if you have wheezing, experience other asthma symptoms, or if you become dizzy or faint. In clinical trials of Xeomin® for the treatment of frown lines between the eyebrows, headache was the most common side effect. Xeomin® may cause loss of strength or general muscle weakness, blurred vision, or drooping eyelids within hours to weeks of taking Xeomin®. If this happens, do not drive a car, operate machinery, or do other dangerous activities. Tell your doctor if you have any side effect that bothers you or that does not subside. These are not all of the possible side effects of Xeomin®. For more information, see Full Prescribing Information including Medication Guide, or ask your doctor.

I’M CONCERNED WITH LOOKING OVERDONE.

Looking overdone is a common concern among individuals considering an in-office treatment for moderate to severe frown lines, forehead lines, or crow’s feet. Talk to your licensed provider. Talk through every concern you have, until you feel comfortable. Your provider, who is experienced in facial anatomy, can determine the right options for you to meet your aesthetic goal.

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XEOMIN® (incobotulinumtoxinA) IMPORTANT CONSUMER SAFETY INFORMATION

Read the Medication Guide before you start receiving XEOMIN (Zeo-min) and each time XEOMIN is given to you as there may be new information. The risk information provided here is not comprehensive.

To learn more:

  • Talk to your health care provider or pharmacist
  • Visit www.xeominaesthetic.com to obtain the Full Prescribing Information and Medication Guide
  • Call 1-866-862-1211

Uses: XEOMIN is a prescription medicine that is injected into muscles and used to improve the look of moderate to severe upper facial lines (frown lines, forehead lines, and crow’s feet) in adults for a short period of time (temporary). Please see additional Important Safety Information below and Full Prescribing Information and Medication Guide at XeominAesthetic.com.

Warnings: XEOMIN may cause serious side effects that can be life threatening. Call your doctor or get medical help right away if you have any of these problems anytime (hours to weeks) after treatment with XEOMIN:

  • Problems with swallowing, speaking, or breathing can happen within hours to weeks after an injection of XEOMIN if the muscles that you use to breathe and swallow become weak. Death can happen as a complication if you have severe problems with swallowing or breathing after treatment with XEOMIN.
    • People with certain breathing problems may need to use muscles in their neck to help them breathe and may be at greater risk for serious breathing problems with XEOMIN.
    • Swallowing problems may last for several months, and during that time you may need a feeding tube to receive food and water. If swallowing problems are severe, food or liquids may go into your lungs. People who already have swallowing or breathing problems before receiving XEOMIN have the highest risk of getting these problems.
  • Spread of toxin effects. In some cases, the effect of botulinum toxin may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism. The symptoms of botulism include: loss of strength and muscle weakness all over the body, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, trouble swallowing.

These symptoms can happen hours to weeks after you receive an injection of XEOMIN. These problems could make it unsafe for you to drive a car or do other dangerous activities. 

Do not use XEOMIN if you are allergic to XEOMIN or any of the ingredients in XEOMIN (see the end of this Guide for a list of ingredients in XEOMIN), had an allergic reaction to any other botulinum toxin products such as rimabotulinumtoxinB (MYOBLOC®), onabotulinumtoxinA (BOTOX®, BOTOX® COSMETIC), or abobotulinumtoxinA (DYSPORT®) or have a skin infection at the planned injection site.

Before receiving XEOMIN, tell your doctor about all of your medical conditions, including if you:

  • have a disease that affects your muscles and nerves (such as amyotrophic lateral sclerosis [ALS or Lou Gehrig’s disease], myasthenia gravis or Lambert-Eaton syndrome)
  • have had any side effect from any other botulinum toxin in the past
  • have a breathing problem such as asthma or emphysema
  • have a history of swallowing problems or inhaling food or fluid into your lungs (aspiration)
  • have bleeding problems
  • have drooping eyelids
  • have plans to have surgery
  • have had surgery on your face
  • are pregnant or plan to become pregnant. It is not known if XEOMIN can harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if XEOMIN passes into breast milk.

Tell your doctor about all of the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Talk to your doctor before you take any new medicines after you receive XEOMIN.

Using XEOMIN with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received XEOMIN in the past. Especially tell your doctor if you 

  • have received any other botulinum toxin product in the last four months
  • have received injections of botulinum toxin such as rimabotulinumtoxinB (MYOBLOC®), onabotulinumtoxinA (BOTOX®, BOTOX® COSMETIC) and abobotulinumtoxinA (DYSPORT®) in the past. Be sure your doctor knows exactly which product you received. The dose of XEOMIN may be different from other botulinum toxin products that you have received.
  • have recently received an antibiotic by injection
  • take muscle relaxants
  • take an allergy or cold medicine
  • take a sleep medicine

Ask your doctor if you are not sure if your medicine is one that is listed above. Know the medicines you take. Keep a list of your medicines with you to show your doctor and pharmacist each time you get a new medicine.

Possible Side Effects

XEOMIN can cause serious side effects that can be life threatening including allergic reactions. Symptoms of an allergic reaction to XEOMIN may include: itching, rash, redness, swelling, wheezing, asthma symptoms, or dizziness or feeling faint. Tell your doctor or get medical help right away if you get wheezing or asthma symptoms, or if you get dizzy or faint. See “Warnings.”

The most common side effect of XEOMIN in people with upper facial lines include:

  • injection site bruising

These are not all the possible side effects of XEOMIN. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit MedWatch or call 1-800-FDA-1088.

General information about the safe and effective use of XEOMIN

Medicines are sometimes prescribed for purposes other than those listed in a Medication Guide. You can ask your pharmacist or doctor for information about XEOMIN that is written for health professionals.

Active Ingredient: botulinum toxin type A

Inactive Ingredients: human albumin and sucrose

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